An immersive micro-manipulation system using real-time 3D imaging microscope and 3D operation interface for high-speed and accurate micro-manipulation

Abstract The use of intracytoplasmic sperm injection (ICSI), an assisted reproductive technique (ART), is increasing widely. ICSI currently performed by specially skilled embryologists. However, with the demand for ART, shortage embryologists has become a problem. Therefore, we propose immersive micromanipulation system that requires no special skills efficient and accurate micromanipulation. Our proposed composed real-time three-dimensional (3D) imaging microscope 3D operation interfaces. interfaces are stationary pen-type or wearable glove-type In this system, operator wearing head-mounted display (HMD) using immersed in virtual space. can move pipettes interface freely change viewpoint. We verified improves speed accuracy operating pipette through two types experiments subjects.